Undenatured Collagen 2 Powder (en inglés)

¿Qué es Undenatured Collagen 2?

El colágeno tipo II no desnaturalizado, también conocido como UC-II, es un colágeno tipo II extraído de cartílago animal utilizando una tecnología de extracción de baja temperatura patentque retiene la estructura completa de triple héy la actividad biológica. UC-II es el colágeno de tipo II que tiene el mayor parecido estructural al cartílago articular de humanos y animales en la naturaleza. Muchos estudios han demostrado que el UC-II juega un papel muy importante en la eliminación de la inflamación de las articulaciones y la mejora del dolor articular y otros síntomas.

El colágeno tipo II es otro miembro importante de la familia del colágeno. A diferencia del colágeno tipo I, el colágeno tipo II consiste de tres cadenas alfa, cada una conteniendo residuos de 1,464 aminoácidos, formando una estructura heliespecial. El colágeno tipo II se encuentra principalmente en el tejido del cartílago articular.

La tecnología de Green Spring suministra colágeno tipo II no desnaturalizado, que se obtiene mediante el uso de cartílago de pollo como materia prima, y la tecnología de extracción a baja temperatura, que mantiene intacta la estructura de triple hédel colágeno macromolecular. Comparado con otros métodos, el colágeno extraído retiene más de la estructura de hétriple no desnature e importantes regiones de Unión bioactivas llamadas epítopos en la hétriple del colágeno. Son estos epítopos los que dan colágeno no desnaturalizado tipo II su mecanismo único de acción, provocando la reparación y reconstrucción del cartílago articular.

Green Spring Technology es una empresa de biotecnología líder en China. Organiza su producción de acuerdo con ISO, HACCP y otras normas de calidad. Ha pasado Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, y muchas otras certificaciones. Con un excelente equipo de i + d, un equipo de producción experimentado y un equipo de ventas profesional, Green Spring puede proporcionar nutracéuticos profesionales, ingredientes alimentarios y soluciones.

Especificaciones: 

Reglamento:

Se ajusta a la normativa de la UE.

Benefits:

Beneficial for Joint Degeneration

A study in a rabbit model of osteoarthritis highlighted the role of a combined solution of chondroitin sulfate, glucosamine, sodium hyaluronate, and natural type II collagen in maintaining joint health. When natural non-denatured type II collagen was added to the glucosamine solution, articular cartilage degradation was significantly reduced and cartilage appearance and structure improved. The joint condition of the natural non-denatured type II collagen experimental group was also closer to that of healthy joints compared to the control group.

May Improve Knee Discomfort

In a randomized controlled study exploring the efficacy of natural non-denatured type II collagen in patients with osteoarthritis of the knee, a three-month intervention (with paracetamol) significantly improved pain compared to a paracetamol-only group. The results showed that the group containing natural non-denatured type II collagen performed better than the control group without the product.

Beneficial for Osteoarthritis

A retrospective observational study of patients with osteoarthritis found that chondroitin sulfate and glucosamine had beneficial effects in reducing cartilage degradation and osteoarthritis progression. The addition of natural non-denatured type II collagen produced better results than the control group using chondroitin sulfate and glucosamine alone.

Improves Mobility

Non-denatured type II collagen is a dietary supplement ingredient that has been shown in studies to support bone and joint health by relieving symptoms of stiffness and discomfort, as well as improving mobility. Hydrolyzed or denatured collagen is a peptide component of collagen that has been broken down enzymatically, by heat or pH changes. In contrast, non-denatured type II collagen retains its natural triple-helical conformation and has a molecular weight of approximately 300 kDa, while collagen hydrolysates have a molecular weight range of 2 to 9 kDa.

The structures are different and have different mechanisms of action. Hydrolyzed collagen is more readily absorbed due to its lower molecular weight and is therefore thought to aid cartilage regeneration by providing the raw material for collagen synthesis. In contrast, preclinical studies have shown that non-denatured collagen influences humoral and cellular immune responses through interactions with gut-associated lymphoid tissue (GALT) during oral tolerance.

Applications:

For Healthcare Products:

Discovered in the early 1970s and isolated from chicken cartilage tissue by MILLER, non-denatured type II collagen is now widely used as a nutritional supplement worldwide. In Japan, non-denatured type II collagen has been approved as a functional food claim for joint improvement. In China, non-denatured type II collagen (renamed cartilage powder containing type II collagen) was approved by the National Health Commission in 2016 to be manufactured and operated as a general food product. Some of the sports health brands already in use are Vibramax, Calcium Elite, and others.