Polvo de diosgenina

¿Qué es la diosgenina?

La diosgenina, comúnmente conocida como diosgenina, es un tipo de diosgenesterosintetiznaturalmente por las plantas y ampliamente presente en los tubérculos de las leguminy Dioscoreaceae. Es una importante materia prima para la síntesis de medicamentos esteroides hormon. Tiene muchos efectos farmacológicos notables, tales como antitumoral, anti-inflam, antioxidante, y tiene un alto valor medicinal.

La primavera verde proporciona el polvo de diosgenina extraído de tubérculos silvestres de ñame. Es una DHEA natural (dehidroepiandrosterona), que puede promover el metabolismo de las células epidérmicas de la piel, mejorar la función hidratante de la piel, y también ayudar a mejorar el físico.

Especificaciones: 

Reglamento:

Se ajusta a la normativa de la UE.

Benefits:

Antitumor Activity

In vivo and in vitro studies have shown that diosgenin has cytotoxicity to a variety of tumor cells, including breast cancer cells, colon cancer cells, prostate cancer cells, lung cancer cells, gastric cancer cells, Osteosarcoma cells, etc. It can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking cell cycle, and anti-tumor metastasis.

Hepatoprotective Effect

Diosgenin powder can effectively inhibit the cell viability of HSC-T6, LX-2, and primary rat hepatic stellate cells (HSCs), while liver cells are not affected. Diosgenin also has a good protective effect on alcoholic liver injury, which is achieved by reducing oxidative stress, the production of inflammatory cytokines, cell apoptosis, and liver steatosis.

Hypoglycemic Effect

The combination of NPH insulin and diosgenin in the treatment of elderly type 2 diabetes is more effective in reducing blood sugar with good safety, which may be related to the reduction of Glycated hemoglobin formation.

Anti Osteoporosis Effect

Dioscin can promote the proliferation of osteoblasts and inhibit the formation of Osteoclast. Research has shown that after diosgenin treatment of MC3T3-E1 cells, ER- α、 ER- β、 Lrp5 β- The expression of both catenin and Bcl-2 proteins increased, and the ratio of OPG/RANKL increased, depending on the LRP5 pathway, thereby promoting osteoblast proliferation.

Applications:

Pharmaceutical Intermediate:

Diosgenin powder is an important steroidal saponin and an important raw material for Semisynthesis steroidal compounds.