Extracto de hoja de Loquat ácido corosólico en polvo al 10%

¿Qué es el polvo de ácido corosólico del extracto de la hoja de Loquat?

El extracto de la hoja de loqueta en polvo de ácido corosólico se refiere al ingrediente activo efectivo en polvo de ácido corosólico extraído del talseco y las hojas de loqueta (Eribotrya japonica (Thunb) Lindl), familia Rosaceae. Los resultados de los experimentos in vitro e in vivo muestran que el ácido corosólico promueve la absorción y utilización de la glucosa por las células a través de la excitación del transporte de glucosa, logrando así su efecto hipoglicémico. El efecto excitatorio del ácido corosólico en el transporte de glucosa es similar al de la insulina, por lo tanto, el ácido corosólico también se conoce como insulina vegetal.

El ácido corosólico puede existir libremente en las plantas o en forma de saponinas. En las plantas, a menudo coexiste con su isómero ácido espino (2α -ácido hidroxyoleanólico), que es estructural y químicamente similar y difícil de separar.

El polvo de ácido corosólico del 10% suministrado por la tecnología Green Spring es un tipo de ingrediente activo vegetal efectivo que se produce mediante la extracción, cristalización y secado de las hojas de la hoja de Loquat de alta calidad, con alta pureza, sin residuos de pesticidas, bajo residuo de disolvente y se ha utilizado como materia prima de productos para el cuidado de la salud.

Green Spring siempre se ha comprometido a proporcionar a los clientes extractos de plantas naturales, seguros y orgánicos. Organizamos nuestra producción de acuerdo con las normas ISO, HACCP y otras normas de calidad. Se ha establecido un sistema de trazabilidad perfecto, todos los productos son trazables, y cada producto desde el origen hasta el producto terminado tiene pruebas detalladas e informes de producción, para garantizar que cada eslabdel proceso de producción es controlable y trazable. Hemos aprobado Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, y muchas otras certificaciones. Podemos proporcionar informes de prueba autorizados de terceros.

Especificaciones:

Normativa:

Se ajusta a la normativa de la UE.

Benefits:

Hypoglycaemic

Loquat Leaf Extract Corosolic Acid Powder has the ability to lower blood glucose, regulate lipid metabolism, and improve diabetes. Corosolic acid can reverse the pathological process of diabetes mellitus by regulating the metabolic interference pathway; it can enhance the cellular uptake of glucose, impair the hydrolysis of sucrose and starch, and reduce the regulation of glucose and lipid metabolism; and lower blood glucose by the inhibitory effect of α-glucosidase, and so on.

Corosolic acid has a completely new pathway when it comes to cellular glucose transport proteins, which absorb glucose into the body's muscles and control blood sugar levels. In addition, corosolic acid inhibits the body's mechanism for making glucose in a process called gluconeogenesis. This mechanism works better to lower blood sugar levels in the body.

Antioxidant

Loquat leaf extract Corosolic acid effectively inhibited Cu2+-induced oxidation of human low-density lipoprotein (LDL) in vitro, protected aortic endothelial cells (HAECs) from AAPH-induced oxidative damage by free radicals, and preserved the integrity of cellular structure. The mechanism is likely to be achieved by increasing antioxidant enzymes such as SOD and glutathione peroxidase (GSH-PX) in the cells.

Anti-inflammatory

In a lipopolysaccharide-induced inflammation model constructed in RAW264.7 cells, loquat leaf extract inhibited the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX-2), and its anti-inflammatory effects were associated with the down-regulation of NF-κB and extracellular-regulated protein kinases (ERKs), p38 mitogen-activated protein kinases (p38 MAPKs), and stress-activated protein kinases (JNKs) protein expressions. ) protein expression is associated. Corosolic acid in loquat leaves plays a role in the treatment of chronic bronchitis (CB) by inhibiting lipopolysaccharide (LPS)-induced IL-8 production and NF-κB activation, and inhibiting i NOS mRNA expression.

Hepatoprotective

Loquat leaf extract ursolic acid powder inhibited the proliferation of HSC-T6 cells cultured in vitro and decreased ECM secretion. Its mechanism of action may be related to the up-regulation of peroxisome proliferator-activated receptor-γ (PPAR-γ) gene and protein expression, and the down-regulation of TGF-β1 gene and protein expression of loquat leaf ursolic acid; loquat leaf ursolic acid exerts hepatoprotective and anti-hepatocellular fibrotic effects by inhibiting hepatic stellate cell activation.

Applications:

For Health Products:

Corosolic acid powder, as a new plant drug against obesity and type II diabetes and functional natural health food pharmaceutical raw materials, has become a popular product in the market; the natural product has been listed as a nutritional supplement in the United States, while conducting phase III clinical trials for the treatment of diabetes, and will be certified by the FDA in the near future. Its effect for the treatment of diabetes mellitus is comparable to that of insulin injection, with the advantages of significant oral effect, small toxic side effects, easy of use, etc. The effect is comparable to that of insulin injection.