El 99% de péptido de cobre GHK polvo

¿Qué es el GHK en polvo de péptido de cobre?

El péptido de cobre GHK es un complejo formado por la combinación de un polipéptido (tripéptido 1) compuesto de glicil-l-histoacil-l-lisina e iones de cobre. Debido a su apariencia azul, es comúnmente conocido como péptido de cobre (GHK-Cu), también conocido como tripéptido 1 de cobre.

En 1973, el Dr. Loren Pickart de UCSF, EE.UU., aisltripéptido 1 (GHK) a partir de suero humano, un péptido hecho por el ser humano que consiste en glicina, histidina y lisina, que inicialmente atrajo la atención en la comunidad farmacológica debido a su capacidad de afectar la supervivencia de los hepatoci. Estudios posteriores revelaron que el tripéptido 1 es un quelante extremadamente fuerte de iones metálicos, formando un complejo azul estable con iones de cobre, el péptido de cobre azul (GHK-Cu).

El péptido de cobre GHK es uno de los pocos componentes péptidos que pueden compliciones metálicos y puede ser utilizado como un portador para transportar iones de cobre a las zonas dañadas de la piel, ejerciendo así funciones de reparación eficientes. Además, el tripéptido 1 es un péptido señal natural en la piel, que puede activar la regeneración del colágeno en la piel y ejercer efectos anti-envejecimiento.

Debido a su excelente efecto de cuidado de la piel, el péptido de cobre GHK ha sido utilizado durante mucho tiempo por varios fabricantes de cosméticos conocidos en sus productos, y por lo general se encuentra en productos de alta gama. El polvo de GHK es seguro, suave y no irritante, lo que lo hace mejor que muchos otros ingredientes anti-arrugas de su tipo. El polvo de GHK también tiene una variedad de efectos, incluyendo antioxidantes, anti-envejecimiento y anti-inflamatorios, que pueden tener múltiples efectos sobre la piel.

La tecnología de primavera verde suministra el El 99% de cobre péptido GHK en polvo con alta pureza, sin residuos de disolvente, y sin residuos de pesticidas, que cumple con las normas internacionales de la farmacopea europea, la farmacopea americana, la farmacopea japonesa y así sucesivamente.

Fundada en 2000, Green Spring Technology se ha comprometido a proporcionar a los clientes extractos de plantas naturales, seguros y orgánicos. Todos los productos que ofrecemos se fabrican con los m ã ¡S altos est ã ¡Ndares internacionales de la industria, cumpliendo con la UE EC396, UE 2023/915 y los m ã ¡S altos est ã ¡Ndares de residuos de disolventes. Tenemos un sistema de gestión de calidad sistemático y organizamos la producción en estricta conformidad con ISO, HACCP y otras normas de calidad. Hemos aprobado Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO y muchas otras certificaciones.

Especificaciones: 

Normativa:

Se ajusta a la normativa de la UE.

Benefits:

Anti-Inflammatory, Antioxidant

Scientists investigated the effect of GHK-Cu powder on reactive oxygen species (ROS) and superoxide dismutase SOD activity in LPS-induced cells. The results showed a significant reduction in ROS production after pretreatment with Copper Peptide GHK at 1, 5, and 10 μM. SOD activity was significantly reduced by approximately 19% in LPS-treated cells, and increased to near control levels in cells pretreated with GHK-Cu (1, 5, and 10 μM).

To determine whether GHK-Cu reduced the release of inflammatory cytokines, the levels of TNF-α and IL-6 were confirmed by ELISA. The results showed that cells pretreated with 10 μM Copper Peptide GHK significantly reduced the secretion of these inflammatory molecules. Thus blue copper peptide reduced ROS induced by LPS and increased SOD activity while reducing the release of pro-inflammatory factors to achieve anti-inflammatory and antioxidant effects.

Promoting Hair Growth

Mouse experiments were conducted to observe the effects of the Copper Peptide GHK on hair growth in mice with the alopecia model, while liposomes of blue copper peptide (CHK-Cu) were prepared to promote transdermal absorption and maintain the advantages of maintaining a high concentration of the drug on the skin. The mice were randomly divided into 3 groups of 10 mice each, namely CHK-Cu liposome group, CHK-Cu group, and control group, and the hair growth was observed by different treatments on the hair loss area.

The results showed shorter hair growth time in the CHK-Cu liposome group and CHK-Cu group compared to the control group. light hairs grew all over the depilated area on day 6 in the CHK-Cu liposome group. On day 14, the hairs were more uniform and thicker than those in the CHK-Cu group and the control group, and the hair growth area and length were also better. Observations on the back skin of mice showed that the subcutaneous vascular network was rich and thicker in the CHK-Cu liposome group and CHK-Cu group mice, which was not obvious in the control group. Meanwhile, compared with the control group, the hair follicles in the CHK-Cu liposome group and CHK-Cu group were more fully developed and more numerous. Skin section samples were taken for hair follicle counting, and the number of hair follicles increased in both the GHK-Cu group and the GHK-Cu liposome group of mice compared with the control group, and the difference was statistically significant (P<0.05).

The experiments confirmed that nanoscale liposomes can effectively encapsulate the Copper Peptide GHK powder as well as have a better hair growth effect, which provides ideas for the development of new topical drugs for the treatment of hair loss.

Skin Tissue Repair

Copper Peptide GHK powder is a biologically active regulator naturally occurring on the alpha 2(I) chain of type I collagen in the extracellular matrix (ECM), which is released after skin damage and is an early signal for tissue repair. In addition, endothelial cells express SPARC, a stromal-type cell-secreted glycoprotein, which is degraded to produce GHK and is thought to be a source of serum GHK.

Copper ions are trace elements required for a variety of enzymatic reactions in the human body. The amount of divalent copper ions in human plasma is about 1 μg/mL, with more than 95% present in plasma cuprocyanin and the remaining 5% bound to other molecules (e.g., albumin, histidine, etc.). Due to its high affinity for copper ions, Copper Peptide GHK antagonises other molecules, competes with them for the complexation of copper ions, and acts as a carrier to deliver copper ions to the site of injury, promoting wound healing and tissue repair.

Anti-Aging & Wrinkle Removal

GHK-Cu powder can effectively enhance the functionality of fibroblasts and stimulate fibroblasts to synthesise ECM components such as glycosaminoglycans, proteoglycans, collagen, elastin, etc., to remodel the skin structure. In addition, GHK-Cu also promotes the expression of matrix metalloproteinases MMP-2, MMP-9, and their tissue inhibitors TIMPs. By regulating the activities of MMPs and TIMPs, GHK-Cu can help maintain the balance between matrix decomposition and synthesis, accelerate tissue remodeling, and improve the appearance of aging skin.

Antioxidant and Anti-Inflammatory

Studies have shown that GHK-Cu powder can inhibit inflammation by lowering the levels of acute inflammatory cytokines such as TGF-β and TNF-α. In addition, by providing copper ions to the tissues, GHK-Cu can enhance the activity of superoxide dismutase, thereby inhibiting the generation of reactive oxygen radicals and achieving antioxidant efficacy.

Applications:

In Cosmetics:

Copper Peptide GHK acts on the dermis to promote the synthesis of extracellular matrix, such as collagen and glycosaminoglycans, resulting in thicker, firmer skin. It also stimulates fibroblast synthesis, promotes collagen and elastin neogenesis, increases blood vessel growth and anti-oxidant power, and repairs damage quickly. In high-end skincare products, Complex Copper Peptide GHK Powder can repair DNA damage, dismantle abnormal collagen fibres that form scars and wrinkles, and rebuild normal pattern proteins, with excellent repair and anti-aging effects.